Mesenchymal stem cells overexpressing IL-35: a novel immunosuppressive strategy and therapeutic target for inducing transplant tolerance

Inducing donor-specific immunological tolerance, which avoids the complications of long-term immunosuppression, is an important goal in organ transplantation. Interleukin-35 (IL-35), a cytokine identified in 2007, is mainly secreted by regulatory T cells (Tregs) and is essential for Tregs to exert t...

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Detalles Bibliográficos
Autores principales: Guo, Hao, Li, Baozhu, Wang, Wei, Zhao, Na, Gao, Haopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158805/
https://www.ncbi.nlm.nih.gov/pubmed/30257721
http://dx.doi.org/10.1186/s13287-018-0988-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158805/
https://www.ncbi.nlm.nih.gov/pubmed/30257721
http://dx.doi.org/10.1186/s13287-018-0988-9

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