Addition of triple negativity of breast cancer as an indicator for germline mutations in predisposing genes increases sensitivity of clinical selection criteria

BACKGROUND: Breast cancer is the most common cancer in women. 12–15% of all tumors are triple-negative breast cancers (TNBC). So far, TNBC has been mainly associated with mutations in BRCA1. The presence of other predisposing genes seems likely since DNA damage repair is a complex process that invol...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoyer, Juliane, Vasileiou, Georgia, Uebe, Steffen, Wunderle, Marius, Kraus, Cornelia, Fasching, Peter A., Thiel, Christian T., Hartmann, Arndt, Beckmann, Matthias W., Lux, Michael P., Reis, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158817/
https://www.ncbi.nlm.nih.gov/pubmed/30257646
http://dx.doi.org/10.1186/s12885-018-4821-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158817/
https://www.ncbi.nlm.nih.gov/pubmed/30257646
http://dx.doi.org/10.1186/s12885-018-4821-8

Ejemplares similares