Cargando…

Erythrocyte-binding assays reveal higher binding of Plasmodium knowlesi Duffy binding protein to human Fy(a+/b+) erythrocytes than to Fy(a+/b-) erythrocytes

BACKGROUND: The merozoite of the zoonotic Plasmodium knowlesi invades human erythrocytes via the binding of its Duffy binding protein (PkDBPαII) to the Duffy antigen on the eythrocytes. The Duffy antigen has two immunologically distinct forms, Fy(a) and Fy(b). In this study, the erythrocyte-binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Fong, Mun Yik, Cheong, Fei Wen, Lau, Yee Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158824/
https://www.ncbi.nlm.nih.gov/pubmed/30257710
http://dx.doi.org/10.1186/s13071-018-3118-8