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Erythrocyte-binding assays reveal higher binding of Plasmodium knowlesi Duffy binding protein to human Fy(a+/b+) erythrocytes than to Fy(a+/b-) erythrocytes
BACKGROUND: The merozoite of the zoonotic Plasmodium knowlesi invades human erythrocytes via the binding of its Duffy binding protein (PkDBPαII) to the Duffy antigen on the eythrocytes. The Duffy antigen has two immunologically distinct forms, Fy(a) and Fy(b). In this study, the erythrocyte-binding...
Autores principales: | Fong, Mun Yik, Cheong, Fei Wen, Lau, Yee Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158824/ https://www.ncbi.nlm.nih.gov/pubmed/30257710 http://dx.doi.org/10.1186/s13071-018-3118-8 |
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