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Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response
BACKGROUND: Patient-derived organoids and xenografts (PDXs) have emerged as powerful models in functional diagnostics with high predictive power for anticancer drug response. However, limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followed by tes...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158900/ https://www.ncbi.nlm.nih.gov/pubmed/30257718 http://dx.doi.org/10.1186/s40880-018-0329-5 |