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Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response

BACKGROUND: Patient-derived organoids and xenografts (PDXs) have emerged as powerful models in functional diagnostics with high predictive power for anticancer drug response. However, limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followed by tes...

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Detalles Bibliográficos
Autores principales: Zhang, Feifei, Wang, Wenjie, Long, Yuan, Liu, Hui, Cheng, Jijun, Guo, Lin, Li, Rongyu, Meng, Chao, Yu, Shan, Zhao, Qingchuan, Lu, Shun, Wang, Lili, Wang, Haitao, Wen, Danyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158900/
https://www.ncbi.nlm.nih.gov/pubmed/30257718
http://dx.doi.org/10.1186/s40880-018-0329-5