Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02

Among patients treated with the anticonvulsive and psychotropic drug carbamazepine (CBZ), approximately 10% develop severe and life-threatening adverse drug reactions. These immunological conditions are resolved upon withdrawal of the medicament, suggesting that the drug does not manifest in the bod...

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Detalles Bibliográficos
Autores principales: Simper, Gwendolin S., Hò, Gia-Gia T., Celik, Alexander A., Huyton, Trevor, Kuhn, Joachim, Kunze-Schumacher, Heike, Blasczyk, Rainer, Bade-Döding, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158965/
https://www.ncbi.nlm.nih.gov/pubmed/30302345
http://dx.doi.org/10.1155/2018/5086503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158965/
https://www.ncbi.nlm.nih.gov/pubmed/30302345
http://dx.doi.org/10.1155/2018/5086503

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