Cargando…

Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02

Among patients treated with the anticonvulsive and psychotropic drug carbamazepine (CBZ), approximately 10% develop severe and life-threatening adverse drug reactions. These immunological conditions are resolved upon withdrawal of the medicament, suggesting that the drug does not manifest in the bod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simper, Gwendolin S., Hò, Gia-Gia T., Celik, Alexander A., Huyton, Trevor, Kuhn, Joachim, Kunze-Schumacher, Heike, Blasczyk, Rainer, Bade-Döding, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158965/ https://www.ncbi.nlm.nih.gov/pubmed/30302345 http://dx.doi.org/10.1155/2018/5086503

Ejemplares similares

The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity
por: Simper, Gwendolin S., et al.
Publicado: (2019)

HLA-B*57:01/Carbamazepine-10,11-Epoxide Association Triggers Upregulation of the NFκB and JAK/STAT Pathways
por: Haukamp, Funmilola Josephine, et al.
Publicado: (2023)

Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion
por: Russell, Jason L., et al.
Publicado: (2015)

NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain
por: Hò, Gia-Gia T., et al.
Publicado: (2020)

Deproteinization as a Rapid Method of Saliva Purification for the Determination of Carbamazepine and Carbamazepine-10,11 Epoxide
por: Dziurkowska, Ewelina, et al.
Publicado: (2020)

HLA-E: Presentation of a Broader Peptide Repertoire Impacts the Cellular Immune Response—Implications on HSCT Outcome
por: Kraemer, Thomas, et al.
Publicado: (2015)

Releasing the concept of HLA‐allele specific peptide anchors in viral infections: A non‐canonical naturally presented human cytomegalovirus‐derived HLA‐A*24:02 restricted peptide drives exquisite immunogenicity
por: Pump, Wiebke C., et al.
Publicado: (2019)

HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues
por: Hò, Gia-Gia T., et al.
Publicado: (2019)

HLA-G peptide preferences change in transformed cells: impact on the binding motif
por: Celik, Alexander A., et al.
Publicado: (2018)

The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch
por: Celik, Alexander A., et al.
Publicado: (2015)

Understanding the obstacle of incompatibility at residue 156 within HLA-B*35 subtypes
por: Manandhar, Trishna, et al.
Publicado: (2016)

Polymorphic Phase Transitions in Carbamazepine and 10,11‐Dihydrocarbamazepine
por: Clout, Alexander E., et al.
Publicado: (2018)

Evaluation of Carbamazepine (CBZ) Supersaturatable Self-Microemulsifying (S-SMEDDS) Formulation In-vitro and In-vivo
por: Nan, Zhang, et al.
Publicado: (2012)

Preliminarily Analysis of Carbamazepine (CBZ) C(0) in Patients Visited Isfahan Epileptic Clinics
por: Tolou-Ghamari, Zahra, et al.
Publicado: (2013)

A Micropolymorphism Altering the Residue Triad 97/114/156 Determines the Relative Levels of Tapasin Independence and Distinct Peptide Profiles for HLA-A(*)24 Allotypes
por: Badrinath, Soumya, et al.
Publicado: (2014)

Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8(+) T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia
por: Pump, Wiebke C., et al.
Publicado: (2019)

The polymorphism at residue 156 determines the HLA-B*35 restricted peptide repertoire during HCMV infection
por: Abels, Wiebke C., et al.
Publicado: (2018)

Soluble HLA Technology as a Strategy to Evaluate the Impact of HLA Mismatches
por: Kunze-Schumacher, Heike, et al.
Publicado: (2014)

Unravelling the Proteomics of HLA-B*57:01(+) Antigen Presenting Cells during Abacavir Medication
por: Haukamp, Funmilola Josephine, et al.
Publicado: (2022)

HLA-A*31:01 and HLA-B*15:02 as genetic markers for carbamazepine hypersensitivity in children
por: Amstutz, Ursula, et al.
Publicado: (2013)

Carbamazepine Enhances Adipogenesis by Inhibiting Wnt/β-Catenin Expression
por: Im, Dong Uk, et al.
Publicado: (2019)

SCN1A and SCN1B gene polymorphisms and their association with plasma concentrations of carbamazepine and carbamazepine 10, 11 epoxide in Iranian epileptic patients
por: Namazi, Soha, et al.
Publicado: (2015)

Non-Recurrence of Carbamazepine Induced Vitiligo after Rechallenge with Carbamazepine
por: Saeedloo, Masoomeh, et al.
Publicado: (2013)

The HLA-A*31:01 allele: influence on carbamazepine treatment
por: Yip, Vincent Lai Ming, et al.
Publicado: (2017)

Personalizing carbamazepine therapy
por: Mushiroda, Taisei, et al.
Publicado: (2011)

Membranous nephropathy and carbamazepine
por: Sangeetha, B., et al.
Publicado: (2014)

Carbamazepine and Hematological Malignancies
por: Yavaşoğlu, İrfan, et al.
Publicado: (2013)

Carbamazepine-induced angioedema
por: Subramanian, Ansha, et al.
Publicado: (2016)

Acute Carbamazepine Intoxication
por: Gallego, María Dolores Calabria, et al.
Publicado: (2022)

HLA-F Allele-Specific Peptide Restriction Represents an Exceptional Proteomic Footprint
por: Hò, Gia-Gia T., et al.
Publicado: (2019)

The microstructure in the placenta is influenced by the functional diversity of HLA-G allelic variants
por: Stieglitz, F., et al.
Publicado: (2019)

Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary
por: Schwich, Esther, et al.
Publicado: (2020)

Carbamazepine and Electro Convulsive Threshold
por: Goswami, Utpal, et al.
Publicado: (1986)

EXFOLIATIVE DERMATITIS DUE TO CARBAMAZEPINE
por: Jayesh, Kanabar
Publicado: (1999)

TREATMENT OF MANIA WITH CARBAMAZEPINE AND LITHIUM
por: Desai, Nimesh G., et al.
Publicado: (1983)

Effect of esomeprazole on the pharmacokinetics of carbamazepine
por: Medhi, Bikash, et al.
Publicado: (2011)

Carbamazepine-induced dystonia in an adolescent
por: Bansal, Shwetank, et al.
Publicado: (2016)

Which is the best in carbamazepine overdose?
por: Karaman, Kıvanç, et al.
Publicado: (2017)

Nystagmus Associated with Carbamazepine Toxicity
por: Wirfs, Lauran, et al.
Publicado: (2017)

Teratogenic Effects of Carbamazepine in Mice
por: Jose, Manna, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sj8mals5grk9vijgqn9mh4c61b