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Methotrexate-induced Leukoencephalopathy without Typical Restricted Diffusion on Diffusion-weighted Imaging and the Utility of Magnetic Resonance Spectroscopy to Support the Diagnosis

Methotrexate (MTX) is a common antimetabolite agent that is widely used today in treating leukemia, lymphoma, and osteosarcoma. Its use has been associated with leukoencephalopathy causing seizures, paralysis, and even coma. To achieve the best possible outcome, it is important to be able to make a...

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Detalles Bibliográficos
Autores principales: Doan, Ninh, Patel, Mohit, Nguyen, Ha Son, Doan, Hayley, Shabani, Saman, Gelsomino, Michael, Mountoure, Andrew, Janich, Karl, Chitambar, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159078/
https://www.ncbi.nlm.nih.gov/pubmed/30283563
http://dx.doi.org/10.4103/ajns.AJNS_324_16