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Methotrexate-induced Leukoencephalopathy without Typical Restricted Diffusion on Diffusion-weighted Imaging and the Utility of Magnetic Resonance Spectroscopy to Support the Diagnosis
Methotrexate (MTX) is a common antimetabolite agent that is widely used today in treating leukemia, lymphoma, and osteosarcoma. Its use has been associated with leukoencephalopathy causing seizures, paralysis, and even coma. To achieve the best possible outcome, it is important to be able to make a...
Autores principales: | Doan, Ninh, Patel, Mohit, Nguyen, Ha Son, Doan, Hayley, Shabani, Saman, Gelsomino, Michael, Mountoure, Andrew, Janich, Karl, Chitambar, Christopher R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159078/ https://www.ncbi.nlm.nih.gov/pubmed/30283563 http://dx.doi.org/10.4103/ajns.AJNS_324_16 |
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