Nucleoside analogs to manage sequence divergence in nucleic acid amplification and SNP detection

Described here are the synthesis, enzymology and some applications of a purine nucleoside analog (H) designed to have two tautomeric forms, one complementary to thymidine (T), the other complementary to cytidine (C). The performance of H is compared by various metrics to performances of other ‘biver...

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Detalles Bibliográficos
Autores principales: Yang, Zunyi, Kim, Hyo-Joong, Le, Jennifer T, McLendon, Chris, Bradley, Kevin M, Kim, Myong-Sang, Hutter, Daniel, Hoshika, Shuichi, Yaren, Ozlem, Benner, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159519/
https://www.ncbi.nlm.nih.gov/pubmed/29800323
http://dx.doi.org/10.1093/nar/gky392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159519/
https://www.ncbi.nlm.nih.gov/pubmed/29800323
http://dx.doi.org/10.1093/nar/gky392

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