Cargando…
Nucleoside analogs to manage sequence divergence in nucleic acid amplification and SNP detection
Described here are the synthesis, enzymology and some applications of a purine nucleoside analog (H) designed to have two tautomeric forms, one complementary to thymidine (T), the other complementary to cytidine (C). The performance of H is compared by various metrics to performances of other ‘biver...
Autores principales: | Yang, Zunyi, Kim, Hyo-Joong, Le, Jennifer T, McLendon, Chris, Bradley, Kevin M, Kim, Myong-Sang, Hutter, Daniel, Hoshika, Shuichi, Yaren, Ozlem, Benner, Steven A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159519/ https://www.ncbi.nlm.nih.gov/pubmed/29800323 http://dx.doi.org/10.1093/nar/gky392 |
Ejemplares similares
-
Nucleoside alpha-thiotriphosphates, polymerases and the exonuclease III analysis of oligonucleotides containing phosphorothioate linkages
por: Yang, Zunyi, et al.
Publicado: (2007) -
Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting
por: Liu, Lingfeng, et al.
Publicado: (2009) -
Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases
por: Mizrahi, Rena A., et al.
Publicado: (2012) -
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs
por: Huang, Shar-yin N., et al.
Publicado: (2013) -
Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen
por: Biondi, Elisa, et al.
Publicado: (2016)