Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage

Congenital muscular dystrophies (CMDs) are characterized by progressive weakness and degeneration of skeletal muscle. In several forms of CMD, abnormal glycosylation of α-dystroglycan (α-DG) results in conditions collectively known as dystroglycanopathies, which are associated with central nervous s...

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Detalles Bibliográficos
Autores principales: Sudo, Atsushi, Kanagawa, Motoi, Kondo, Mai, Ito, Chiyomi, Kobayashi, Kazuhiro, Endo, Mitsuharu, Minami, Yasuhiro, Aiba, Atsu, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159531/
https://www.ncbi.nlm.nih.gov/pubmed/29360985
http://dx.doi.org/10.1093/hmg/ddy032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159531/
https://www.ncbi.nlm.nih.gov/pubmed/29360985
http://dx.doi.org/10.1093/hmg/ddy032

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