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Deletion of Alzheimer’s Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels

ATP-binding cassette A7 (ABCA7) is a genetic risk factor for late-onset Alzheimer’s disease (AD). It belongs to a group of transporter genes that specializes in regulating lipid transport in the periphery as well as in the brain. ABCA7 has been implicated in a number of roles relating to AD patholog...

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Detalles Bibliográficos
Autores principales: Bhatia, Surabhi, Fu, YuHong, Hsiao, Jen-Hsiang T., Halliday, Glenda M., Kim, Woojin Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159609/
https://www.ncbi.nlm.nih.gov/pubmed/30480241
http://dx.doi.org/10.3233/ADR-170029