Cargando…

Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [(18)F]FDG-μPET Study

BACKGROUND: The Apolipoprotein E (ApoE) alleles ɛ2, ɛ3, and ɛ4 are known to differentially modulate cerebral glucose metabolism and the risk for Alzheimer’s disease (AD) via both amyloid-β (Aβ)-dependent and independent mechanisms. OBJECTIVE: We investigated the influence of ApoE on cerebral glucose...

Descripción completa

Detalles Bibliográficos
Autores principales:	Venzi, Marcello, Tóth, Miklós, Häggkvist, Jenny, Bogstedt, Anna, Rachalski, Adeline, Mattsson, Anna, Frumento, Paolo, Farde, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159693/ https://www.ncbi.nlm.nih.gov/pubmed/30480236 http://dx.doi.org/10.3233/ADR-170006

Ejemplares similares

ABC transporter-dependent brain uptake of the 5-HT(1B) receptor radioligand [(11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig
por: Tóth, Miklós, et al.
Publicado: (2014)

Interaction of APOE4 alleles and PET tau imaging in former contact sport athletes
por: Vasilevskaya, Anna, et al.
Publicado: (2020)

Positron Emission Tomography studies with [(11)C]PBR28 in the Healthy Rodent Brain: Validating SUV as an Outcome Measure of Neuroinflammation
por: Tóth, Miklós, et al.
Publicado: (2015)

Longitudinal [(18)F]FDG-PET/CT analysis of the glucose metabolism in ApoE-deficient mice
por: Kuhla, Angela, et al.
Publicado: (2020)

Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia
por: Salvadó, Gemma, et al.
Publicado: (2021)

Sex differences in gene expression patterns associated with the APOE4 allele
por: Hsu, Michelle, et al.
Publicado: (2019)

Astrocytosis precedes amyloid plaque deposition in Alzheimer APPswe transgenic mouse brain: a correlative positron emission tomography and in vitro imaging study
por: Rodriguez-Vieitez, Elena, et al.
Publicado: (2015)

A FDG-PET Study of Metabolic Networks in Apolipoprotein E ε4 Allele Carriers
por: Yao, Zhijun, et al.
Publicado: (2015)

Murine Gut Microbiome Association With APOE Alleles
por: Parikh, Ishita J., et al.
Publicado: (2020)

The role of hybrid FDG-PET/MRI on decision-making in presurgical evaluation of drug-resistant epilepsy
por: Tóth, Márton, et al.
Publicado: (2021)

FDG-PET in lymphoma
por: Meignan, Michel
Publicado: (2014)

PET-FDG: Impetus
por: Nanni, Cristina
Publicado: (2020)

[(18)F]MPPF and [(18)F]FDG μPET imaging in rats: impact of transport and restraint stress
por: Buchecker, Verena, et al.
Publicado: (2020)

Clinical Perspectives for (18)F-FDG PET Imaging in Pediatric Oncology: Μetabolic Tumor Volume and Radiomics
por: Lyra, Vassiliki, et al.
Publicado: (2022)

APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease
por: Yassine, Hussein N., et al.
Publicado: (2020)

FDG-PET and PET/CT - Part II
por: Takalkar, Amol M, et al.
Publicado: (2008)

Dynamics of the Apo µ-Opioid Receptor in Complex with Gi Protein
por: de Lima, Mira Raya Paula, et al.
Publicado: (2023)

FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels
por: Rubinski, Anna, et al.
Publicado: (2020)

Polygenic Risk Score Analysis of Alzheimer’s Disease in Cases without APOE4 or APOE2 Alleles
por: Escott-Price, V., et al.
Publicado: (2018)

FDG-PET in colorectal cancer
por: de Geus-Oei, Lioe-Fee, et al.
Publicado: (2006)

FDG-PET of Takayasu’s Arteritis
por: Shikino, Kiyoshi, et al.
Publicado: (2014)

FDG-PET/CT in lymphoma
por: D'souza, Maria M, et al.
Publicado: (2013)

FDG-PET and colon cancer
por: Miles, Ken
Publicado: (2015)

Detection of primary sites in unknown primary tumors using FDG-PET or FDG-PET/CT
por: Park, Jong Sun, et al.
Publicado: (2011)

FDG PET-CT: Need for Vigilance in Patients Treated with Bleomycin
por: Paschali, Anna N, et al.
Publicado: (2017)

Protective effect of the APOE-e3 allele in Alzheimer's disease
por: de-Almada, B.V.P., et al.
Publicado: (2011)

Characterization of APOE and TOMM40 allele frequencies in the Japanese population
por: Nishimura, Akira, et al.
Publicado: (2017)

FDG PET or PET/CT in Evaluation of Renal Angiomyolipoma
por: Lin, Chun-Yi, et al.
Publicado: (2013)

FDG-PET Scan: a new Paradigm for Follicular Lymphoma Management
por: Gallamini, Andrea, et al.
Publicado: (2017)

Structural heterogeneity of the μ-opioid receptor’s conformational ensemble in the apo state
por: Sena, Diniz M., et al.
Publicado: (2017)

[18F]FLT and [18F]FDG PET for Non-invasive Treatment Monitoring of the Nicotinamide Phosphoribosyltransferase Inhibitor APO866 in Human Xenografts
por: Munk Jensen, Mette, et al.
Publicado: (2013)

Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein
por: Papaioannou, Ioannis, et al.
Publicado: (2012)

Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis
por: Momkute, Liucija, et al.
Publicado: (2022)

Cerebrovascular Changes and Neurodegeneration Related to Hyperlipidemia: Characteristics of the Human ApoB-100 Transgenic Mice
por: Tóth, Melinda E., et al.
Publicado: (2020)

(18)F-FDG PET/CT Findings in Cytomegalovirus Colitis
por: Kjaer, Anna Sophie L., et al.
Publicado: (2018)

Riedel’s Thyroiditis with Intense FDG Uptake Demonstrated on FDG PET/CT
por: Mansberg, Robert, et al.
Publicado: (2015)

Can FDG-PET/CT replace blind bone marrow biopsy of the posterior iliac crest in Ewing sarcoma?
por: Kasalak, Ömer, et al.
Publicado: (2017)

Predictive and prognostic value of FDG-PET
por: de Geus-Oei, Lioe-Fee, et al.
Publicado: (2008)

Kidney Modelling for FDG Excretion with PET
por: Qiao, Huiting, et al.
Publicado: (2007)

FDG-PET in Follicular Lymphoma Management
por: Bodet-Milin, C., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9ie02hhukk44dpiup4o6q3ml7o