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The Bri2 and Bri3 BRICHOS Domains Interact Differently with Aβ(42) and Alzheimer Amyloid Plaques
Alzheimer’s disease (AD) is the most common form of dementia and there is no successful treatment available. Evidence suggests that fibril formation of the amyloid β-peptide (Aβ) is a major underlying cause of AD, and treatment strategies that reduce the toxic effects of Aβ amyloid are sought for. T...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159705/ https://www.ncbi.nlm.nih.gov/pubmed/30480246 http://dx.doi.org/10.3233/ADR-170051 |