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Prion Protein PRNP: A New Player in Innate Immunity? The Aβ Connection

The prion protein PRNP has been centrally implicated in the transmissible spongiform encephalopathies (TSEs), but its normal physiological role remains obscure. We highlight emerging evidence that PRNP displays antimicrobial activity, inhibiting the replication of multiple viruses, and also interact...

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Detalles Bibliográficos
Autores principales: Lathe, Richard, Darlix, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159716/
https://www.ncbi.nlm.nih.gov/pubmed/30480243
http://dx.doi.org/10.3233/ADR-170037