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Prion Protein PRNP: A New Player in Innate Immunity? The Aβ Connection
The prion protein PRNP has been centrally implicated in the transmissible spongiform encephalopathies (TSEs), but its normal physiological role remains obscure. We highlight emerging evidence that PRNP displays antimicrobial activity, inhibiting the replication of multiple viruses, and also interact...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159716/ https://www.ncbi.nlm.nih.gov/pubmed/30480243 http://dx.doi.org/10.3233/ADR-170037 |