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Efficacy and safety of de-escalation bone- modifying agents for cancer patients with bone metastases: a systematic review and meta-analysis

BACKGROUND: Compared with application of bone-modifying agents (BMAs) every 4 weeks, it is unclear whether 12-weekly de-escalated therapy can be used as a substitute strategy. METHODS: A systematic search of PubMed, EMBASE, and the Cochrane Register of Controlled Trials until November 22, 2017, was...

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Detalles Bibliográficos
Autores principales: Liu, Cun, Wang, Lu, Liu, Lijuan, Zhuang, Jing, Tang, Shifeng, Zhang, Tiansong, Zhou, Chao, Feng, Fubin, Liu, Ruijuan, Zhang, Jinmei, Zhang, Tingting, Gao, Chundi, Li, Huayao, Li, Jia, Sun, Changgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159799/
https://www.ncbi.nlm.nih.gov/pubmed/30288112
http://dx.doi.org/10.2147/CMAR.S176811