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Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Back pain is the #1 cause of years lived with disability worldwide, yet surprisingly little is known regarding the biology underlying this symptom. We conducted a genome-wide association study (GWAS) meta-analysis of chronic back pain (CBP). Adults of European ancestry were included from 15 cohorts...

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Detalles Bibliográficos
Autores principales: Suri, Pradeep, Palmer, Melody R., Tsepilov, Yakov A., Freidin, Maxim B., Boer, Cindy G., Yau, Michelle S., Evans, Daniel S., Gelemanovic, Andrea, Bartz, Traci M., Nethander, Maria, Arbeeva, Liubov, Karssen, Lennart, Neogi, Tuhina, Campbell, Archie, Mellstrom, Dan, Ohlsson, Claes, Marshall, Lynn M., Orwoll, Eric, Uitterlinden, Andre, Rotter, Jerome I., Lauc, Gordan, Psaty, Bruce M., Karlsson, Magnus K., Lane, Nancy E., Jarvik, Gail P., Polasek, Ozren, Hochberg, Marc, Jordan, Joanne M., Van Meurs, Joyce B. J., Jackson, Rebecca, Nielson, Carrie M., Mitchell, Braxton D., Smith, Blair H., Hayward, Caroline, Smith, Nicholas L., Aulchenko, Yurii S., Williams, Frances M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159857/
https://www.ncbi.nlm.nih.gov/pubmed/30261039
http://dx.doi.org/10.1371/journal.pgen.1007601