Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers

Previous pre-clinical studies demonstrated a promising role of alpha-type peroxisome proliferator-activated receptors (PPARα) agonists in decreasing nicotine self-administration and nicotine-seeking behavior in animals. Our goal was to investigate the potential of gemfibrozil, a PPARα agonist, on re...

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Detalles Bibliográficos
Autores principales: Gendy, Marie N. S., Di Ciano, Patricia, Kowalczyk, William J., Barrett, Sean P., George, Tony P., Heishman, Stephen, Le Foll, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160014/
https://www.ncbi.nlm.nih.gov/pubmed/30260990
http://dx.doi.org/10.1371/journal.pone.0201512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160014/
https://www.ncbi.nlm.nih.gov/pubmed/30260990
http://dx.doi.org/10.1371/journal.pone.0201512

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