Cargando…

Designing antibodies against LRRK2-targeted tau epitopes

Phosphorylation of the microtubule associated protein tau is an important modulator of its normal physiological functioning; however, it may also contribute to tau mis-folding and aggregation in neurodegenerative diseases, which are collectively termed tauopathies. As such, the investigations of tau...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamm, Matthew, Ladd, Thomas B., Levites, Yona, Golde, Todd E., Giasson, Benoit I., Lewis, Jada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160062/
https://www.ncbi.nlm.nih.gov/pubmed/30261006
http://dx.doi.org/10.1371/journal.pone.0204367