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Immortalization of common marmoset monkey fibroblasts by piggyBac transposition of hTERT

Following a certain type-specific number of mitotic divisions, terminally differentiated cells undergo proliferative senescence, thwarting efforts to expand different cell populations in vitro for the needs of scientific research or medical therapies. The primary cause of this phenomenon is the prog...

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Detalles Bibliográficos
Autores principales: Petkov, Stoyan, Kahland, Tobias, Shomroni, Orr, Lingner, Thomas, Salinas, Gabriela, Fuchs, Sigrid, Debowski, Katharina, Behr, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160115/
https://www.ncbi.nlm.nih.gov/pubmed/30261016
http://dx.doi.org/10.1371/journal.pone.0204580