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Structural and biochemical characterization of the Cutibacterium acnes exo-β-1,4-mannosidase that targets the N-glycan core of host glycoproteins

Commensal and pathogenic bacteria have evolved efficient enzymatic pathways to feed on host carbohydrates, including protein-linked glycans. Most proteins of the human innate and adaptive immune system are glycoproteins where the glycan is critical for structural and functional integrity. Besides en...

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Detalles Bibliográficos
Autores principales: Reichenbach, Tom, Kalyani, Dayanand, Gandini, Rosaria, Svartström, Olov, Aspeborg, Henrik, Divne, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160142/
https://www.ncbi.nlm.nih.gov/pubmed/30261037
http://dx.doi.org/10.1371/journal.pone.0204703