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The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates

Topoisomerase 3α, a class I topoisomerase, consists of a TOPRIM domain, an active centre and a variable number of zinc-finger domains (ZFDs) at the C-terminus, in multicellular organisms. Whereas the functions of the TOPRIM domain and the active centre are known, the specific role of the ZFDs is sti...

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Detalles Bibliográficos
Autores principales: Dorn, Annika, Röhrig, Sarah, Papp, Kristin, Schröpfer, Susan, Hartung, Frank, Knoll, Alexander, Puchta, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160208/
https://www.ncbi.nlm.nih.gov/pubmed/30222730
http://dx.doi.org/10.1371/journal.pgen.1007674