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MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo

In the sea urchin embryo, specification of the dorsal-ventral axis critically relies on the spatially restricted expression of nodal in the presumptive ventral ectoderm. The ventral restriction of nodal expression requires the activity of the maternal TGF-β ligand Panda but the mechanism by which Pa...

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Detalles Bibliográficos
Autores principales: Molina, M. Dolores, Quirin, Magali, Haillot, Emmanuel, De Crozé, Noémie, Range, Ryan, Rouel, Mathieu, Jimenez, Felipe, Amrouche, Radja, Chessel, Aline, Lepage, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160229/
https://www.ncbi.nlm.nih.gov/pubmed/30222786
http://dx.doi.org/10.1371/journal.pgen.1007621