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Structural principles of SNARE complex recognition by the AAA+ protein NSF

The recycling of SNARE proteins following complex formation and membrane fusion is an essential process in eukaryotic trafficking. A highly conserved AAA+ protein, NSF (N-ethylmaleimide sensitive factor) and an adaptor protein, SNAP (soluble NSF attachment protein), disassemble the SNARE complex. We...

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Detalles Bibliográficos
Autores principales: White, K Ian, Zhao, Minglei, Choi, Ucheor B, Pfuetzner, Richard A, Brunger, Axel T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160233/
https://www.ncbi.nlm.nih.gov/pubmed/30198481
http://dx.doi.org/10.7554/eLife.38888