Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection

Notch ligand Delta-like ligand 4 (DLL4) has been shown to regulate CD4 T-cell differentiation, including regulatory T cells (T(reg)). Epigenetic alterations, which include histone modifications, are critical in cell differentiation decisions. Recent genome-wide studies demonstrated that T(reg) have...

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Detalles Bibliográficos
Autores principales: Ting, Hung-An, de Almeida Nagata, Denise, Rasky, Andrew J, Malinczak, Carrie-Anne, Maillard, Ivan P, Schaller, Matthew A, Lukacs, Nicholas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160345/
https://www.ncbi.nlm.nih.gov/pubmed/30038214
http://dx.doi.org/10.1038/s41385-018-0052-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160345/
https://www.ncbi.nlm.nih.gov/pubmed/30038214
http://dx.doi.org/10.1038/s41385-018-0052-1

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