Implications of Off‐Target Serotoninergic Drug Activity: An Analysis of Serotonin Syndrome Reports Using a Systematic Bioinformatics Approach

STUDY OBJECTIVE: Serotonergic adverse drug events (ADEs) are caused by enhanced intrasynaptic concentrations of 5‐hydroxytryptamine (5‐HT). No systematic process currently exists for evaluating cumulative 5‐HT and off‐target toxicity of serotonergic drugs. The primary study aim was to create a Serot...

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Detalles Bibliográficos
Autores principales: Culbertson, Vaughn L., Rahman, Shaikh E., Bosen, Grayson C., Caylor, Matthew L., Echevarria, Megan M., Xu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160353/
https://www.ncbi.nlm.nih.gov/pubmed/29972695
http://dx.doi.org/10.1002/phar.2163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160353/
https://www.ncbi.nlm.nih.gov/pubmed/29972695
http://dx.doi.org/10.1002/phar.2163

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