Structural insights into modulation and selectivity of transsynaptic neurexin–LRRTM interaction

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) function as postsynaptic organizers that induce excitatory synapses. Neurexins (Nrxns) and heparan sulfate proteoglycans have been identified as presynaptic ligands for LRRTMs. Specifically, LRRTM1 and LRRTM2 bind to the Nrxn splice varian...

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Detalles Bibliográficos
Autores principales: Yamagata, Atsushi, Goto-Ito, Sakurako, Sato, Yusuke, Shiroshima, Tomoko, Maeda, Asami, Watanabe, Masahiko, Saitoh, Takashi, Maenaka, Katsumi, Terada, Tohru, Yoshida, Tomoyuki, Uemura, Takeshi, Fukai, Shuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160412/
https://www.ncbi.nlm.nih.gov/pubmed/30262834
http://dx.doi.org/10.1038/s41467-018-06333-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160412/
https://www.ncbi.nlm.nih.gov/pubmed/30262834
http://dx.doi.org/10.1038/s41467-018-06333-8

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