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RNA modification landscape of the human mitochondrial tRNA(Lys) regulates protein synthesis
Post-transcriptional RNA modifications play a critical role in the pathogenesis of human mitochondrial disorders, but the mechanisms by which specific modifications affect mitochondrial protein synthesis remain poorly understood. Here we used a quantitative RNA sequencing approach to investigate, at...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160436/ https://www.ncbi.nlm.nih.gov/pubmed/30262910 http://dx.doi.org/10.1038/s41467-018-06471-z |