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Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
Increasing evidence suggests that environmental neurotoxicants or misfolded α-synuclein generated by such neurotoxicants are transported from the gastrointestinal tract to the central nervous system via the vagus nerve, triggering degeneration of dopaminergic neurons in the substantia nigra pars com...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160447/ https://www.ncbi.nlm.nih.gov/pubmed/30302391 http://dx.doi.org/10.1038/s41531-018-0066-0 |