AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A

Adaptor protein 4 (AP-4) is an ancient membrane trafficking complex, whose function has largely remained elusive. In humans, AP-4 deficiency causes a severe neurological disorder of unknown aetiology. We apply unbiased proteomic methods, including ‘Dynamic Organellar Maps’, to find proteins whose su...

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Detalles Bibliográficos
Autores principales: Davies, Alexandra K., Itzhak, Daniel N., Edgar, James R., Archuleta, Tara L., Hirst, Jennifer, Jackson, Lauren P., Robinson, Margaret S., Borner, Georg H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160451/
https://www.ncbi.nlm.nih.gov/pubmed/30262884
http://dx.doi.org/10.1038/s41467-018-06172-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160451/
https://www.ncbi.nlm.nih.gov/pubmed/30262884
http://dx.doi.org/10.1038/s41467-018-06172-7

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