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Dynein links engulfment and execution of apoptosis via CED-4/Apaf1 in C. elegans

Apoptosis ensures removal of damaged cells and helps shape organs during development by removing excessive cells. To prevent the intracellular content of the apoptotic cells causing damage to surrounding cells, apoptotic cells are quickly cleared by engulfment. Tight regulation of apoptosis and engu...

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Detalles Bibliográficos
Autores principales: Harders, Rikke Hindsgaul, Morthorst, Tine Hørning, Lande, Anna Dippel, Hesselager, Marianne Overgaard, Mandrup, Ole Aalund, Bendixen, Emøke, Stensballe, Allan, Olsen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160458/
https://www.ncbi.nlm.nih.gov/pubmed/30262881
http://dx.doi.org/10.1038/s41419-018-1067-y