Identification of Peptide Mimotope Ligands for Natalizumab

Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (Veritopes(TM)) that bind natalizumab, a therapeutic mAb ind...

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Detalles Bibliográficos
Autores principales: Ruff, Laura E., Pfeilsticker, Jessica A., Johnsen, Nicholas E., Nocchi, Sarah, Messmer, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160459/
https://www.ncbi.nlm.nih.gov/pubmed/30262856
http://dx.doi.org/10.1038/s41598-018-32832-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160459/
https://www.ncbi.nlm.nih.gov/pubmed/30262856
http://dx.doi.org/10.1038/s41598-018-32832-1

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