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Identification of Peptide Mimotope Ligands for Natalizumab
Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (Veritopes(TM)) that bind natalizumab, a therapeutic mAb ind...
Autores principales: | Ruff, Laura E., Pfeilsticker, Jessica A., Johnsen, Nicholas E., Nocchi, Sarah, Messmer, Bradley T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160459/ https://www.ncbi.nlm.nih.gov/pubmed/30262856 http://dx.doi.org/10.1038/s41598-018-32832-1 |
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