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Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism

Several members of the EPH kinase family and their ligands are involved in blood pressure regulation, and such regulation is often sex- or sex hormone-dependent, based on animal and human genetic studies. EPHB6 gene knockout (KO) in mice leads to hypertension in castrated males but not in un-manipul...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Zhang, Bi-Qi, Raelson, John, Yao, Yu-Mei, Wu, Huan-Dong, Xu, Zao-Xian, Marois-blanchet, Francois-christophe, Tahir, Muhammad Ramzan, Wang, Yujia, Bradley, W. Edward, Luo, Hongyu, Wu, Jiangping, Sheng, Jian-Zhong, Hu, Shen-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160468/
https://www.ncbi.nlm.nih.gov/pubmed/30262919
http://dx.doi.org/10.1038/s41598-018-32836-x