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Serum deprivation/starvation leads to reactivation of HIV-1 in latently infected monocytes via activating ERK/JNK pathway

Despite the high success rate, antiretroviral therapy does not cure the disease completely due to presence of latent viral reservoirs. Although several studies have addressed this issue earlier, the role of serum starvation/deprivation in HIV-1 latency has not been studied. So, we investigated the r...

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Detalles Bibliográficos
Autores principales: Raja, Rameez, Lata, Sneh, Trivedi, Shubhendu, Banerjea, Akhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160481/
https://www.ncbi.nlm.nih.gov/pubmed/30262819
http://dx.doi.org/10.1038/s41598-018-32316-2