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A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcome

In a significant number of cases cancer therapy is followed by a resurgence of more aggressive tumors derived from immature cells. One example is acute myeloid leukemia (AML), where an accumulation of immature cells is responsible for relapse following treatment. We previously demonstrated in chroni...

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Detalles Bibliográficos
Autores principales: Voeltzel, Thibault, Flores-Violante, Mario, Zylbersztejn, Florence, Lefort, Sylvain, Billandon, Marion, Jeanpierre, Sandrine, Joly, Stéphane, Fossard, Gaelle, Milenkov, Milen, Mazurier, Frédéric, Nehme, Ali, Belhabri, Amine, Paubelle, Etienne, Thomas, Xavier, Michallet, Mauricette, Louache, Fawzia, Nicolini, Franck-Emmanuel, Caron de Fromentel, Claude, Maguer-Satta, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160490/
https://www.ncbi.nlm.nih.gov/pubmed/30262802
http://dx.doi.org/10.1038/s41419-018-1042-7