MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth

A major risk factor for colon cancer growth and progression is chronic inflammation. We have shown that the MAPK-activated protein kinase 2 (MK2) pathway is critical for colon tumor growth in colitis-associated and spontaneous colon cancer models. This pathway is known to regulate expression of the...

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Detalles Bibliográficos
Autores principales: Phinney, Brandon B., Ray, Anita L., Peretti, Amanda S., Jerman, Stephanie J., Grim, Carl, Pinchuk, Irina V., Beswick, Ellen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160543/
https://www.ncbi.nlm.nih.gov/pubmed/30298062
http://dx.doi.org/10.3389/fimmu.2018.01857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160543/
https://www.ncbi.nlm.nih.gov/pubmed/30298062
http://dx.doi.org/10.3389/fimmu.2018.01857

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