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MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth

A major risk factor for colon cancer growth and progression is chronic inflammation. We have shown that the MAPK-activated protein kinase 2 (MK2) pathway is critical for colon tumor growth in colitis-associated and spontaneous colon cancer models. This pathway is known to regulate expression of the...

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Detalles Bibliográficos
Autores principales:	Phinney, Brandon B., Ray, Anita L., Peretti, Amanda S., Jerman, Stephanie J., Grim, Carl, Pinchuk, Irina V., Beswick, Ellen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160543/ https://www.ncbi.nlm.nih.gov/pubmed/30298062 http://dx.doi.org/10.3389/fimmu.2018.01857

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