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Evaluation of Chitosan Derivative Microparticles Encapsulating Superparamagnetic Iron Oxide and Doxorubicin as a pH-Sensitive Delivery Carrier in Hepatic Carcinoma Treatment: An in vitro Comparison Study

We developed a novel, pH-sensitive drug delivery microparticle based on N-palmitoyl chitosan (NPCS) to transport the superparamagnetic iron oxide (SPIO) and anticancer drug doxorubicin (DOX). The characteristics of NPCS were characterized through nuclear magnetic resonance. Our results based on test...

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Detalles Bibliográficos
Autores principales: Bai, Meng-Yi, Tang, Sung-Ling, Chuang, Meng-Han, Wang, Ting-Ying, Hong, Po-da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160595/
https://www.ncbi.nlm.nih.gov/pubmed/30298001
http://dx.doi.org/10.3389/fphar.2018.01025