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Functional brain network centrality is related to APOE genotype in cognitively normal elderly

INTRODUCTION: Amyloid plaque deposition in the brain is an early pathological change in Alzheimer's disease (AD), causing disrupted synaptic connections. Brain network disruptions in AD have been demonstrated with eigenvector centrality (EC), a measure that identifies central regions within net...

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Detalles Bibliográficos
Autores principales: Wink, Alle Meije, Tijms, Betty M., ten Kate, Mara, Raspor, Eva, de Munck, Jan C., Altena, Ellemarije, Ecay‐Torres, Mirian, Clerigue, Montserrat, Estanga, Ainara, Garcia‐Sebastian, Maite, Izagirre, Andrea, Martinez‐Lage Alvarez, Pablo, Villanua, Jorge, Barkhof, Frederik, Sanz‐Arigita, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160659/
https://www.ncbi.nlm.nih.gov/pubmed/30136422
http://dx.doi.org/10.1002/brb3.1080