Personalized molecular modeling for pinpointing associations of protein dysfunction and variants associated with hereditary cancer syndromes

BACKGROUND: Although the process of reclassification of a variant of uncertain significance can be complex, they are commonly detected through molecular testing. It often takes years before enough clinical data are acquired, and it can be costly and time‐consuming to perform functional analysis of a...

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Detalles Bibliográficos
Autores principales: Macklin, Sarah, Mohammed, Ahmed, Jackson, Jessica, Hines, Stephanie L., Atwal, Paldeep S., Caulfield, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160717/
https://www.ncbi.nlm.nih.gov/pubmed/30043523
http://dx.doi.org/10.1002/mgg3.447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160717/
https://www.ncbi.nlm.nih.gov/pubmed/30043523
http://dx.doi.org/10.1002/mgg3.447

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