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5-N-Carboxyimino-6-N-chloroaminopyrimidine-2,4(3H)-dione as a hypochlorite-specific oxidation product of uric acid

Although uric acid is known to react with many reactive oxygen species, its specific oxidation products have not been fully characterized. We now report that 5-N-carboxyimino-6-N-chloroaminopyrimidine-2,4(3H)-dione (CCPD) is a hypochlorite (ClO(−))-specific oxidation product of uric acid. The yield...

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Detalles Bibliográficos
Autores principales: Iida, Sayaka, Yamamoto, Yorihiro, Susa, Chisato, Tsukui, Kana, Fujisawa, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160727/
https://www.ncbi.nlm.nih.gov/pubmed/30279617
http://dx.doi.org/10.3164/jcbn.18-6