Cargando…

5-N-Carboxyimino-6-N-chloroaminopyrimidine-2,4(3H)-dione as a hypochlorite-specific oxidation product of uric acid

Although uric acid is known to react with many reactive oxygen species, its specific oxidation products have not been fully characterized. We now report that 5-N-carboxyimino-6-N-chloroaminopyrimidine-2,4(3H)-dione (CCPD) is a hypochlorite (ClO(−))-specific oxidation product of uric acid. The yield...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iida, Sayaka, Yamamoto, Yorihiro, Susa, Chisato, Tsukui, Kana, Fujisawa, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160727/ https://www.ncbi.nlm.nih.gov/pubmed/30279617 http://dx.doi.org/10.3164/jcbn.18-6

Ejemplares similares

Parabanic acid is the singlet oxygen specific oxidation product of uric acid
por: Iida, Sayaka, et al.
Publicado: (2017)

4-Cl-edaravone and (E)-2-chloro-3-[(E)-phenyldiazenyl]-2-butenoic acid are the specific reaction products of edaravone with hypochlorite
por: Amekura, Sakiko, et al.
Publicado: (2020)

Increase of oxidation rate of uric acid by singlet oxygen at higher pH
por: Horinouchi, Rina, et al.
Publicado: (2021)

Riboflavin compounds show NAD(P)H dependent quinone oxidoreductase-like quinone reducing activity
por: Nagase, Midori, et al.
Publicado: (2023)

Orally ingested ubiquinol-10 or ubiquinone-10 reaches the intestinal tract and is absorbed by the small intestine of mice mostly in its original form
por: Kubo, Hiroshi, et al.
Publicado: (2023)

Selective Synthesis and Photoluminescence Study of Pyrazolopyridopyridazine Diones and N-Aminopyrazolopyrrolopyridine Diones
por: Tseng, Ching-Chun, et al.
Publicado: (2020)

Stabilizers of edaravone aqueous solution and their action mechanisms. 1. Sodium bisulfite
por: Tanaka, Masahiko, et al.
Publicado: (2017)

Stabilizers of edaravone aqueous solution and their action mechanisms. 2. Glutathione
por: Tanaka, Masahiko, et al.
Publicado: (2017)

Quinazoline-2,4(1H,3H)-dione
por: Liu, Ge
Publicado: (2008)

Edaravone, a scavenger for multiple reactive oxygen species, reacts with singlet oxygen to yield 2-oxo-3-(phenylhydrazono)-butanoic acid
por: Amekura, Sakiko, et al.
Publicado: (2022)

Uric Acid in Inflammation and the Pathogenesis of Atherosclerosis
por: Kimura, Yoshitaka, et al.
Publicado: (2021)

1H-Benzo[g]pteridine-2,4-dione
por: Uppu, Rao M., et al.
Publicado: (2023)

N-doped carbon dots as robust fluorescent probes for the rapid detection of hypochlorite
por: Wang, Kai, et al.
Publicado: (2022)

A Facile Synthesis of N-H- and N-Substituted Acridine-1,8-diones under Sonic Condition
por: Sudha, S., et al.
Publicado: (2013)

6-Phenyloxane-2,4-dione
por: Slater, Kara A., et al.
Publicado: (2012)

Synthesis of 3-(Pyridin-2-yl)quinazolin-2,4(1H,3H)-diones via Annulation of Anthranilic Esters with N-pyridyl Ureas †
por: Baykova, Svetlana O., et al.
Publicado: (2023)

Quantitation and identification of organic N-chloramines formed in stomach fluid on ingestion of aqueous hypochlorite.
por: Scully, F E, et al.
Publicado: (1986)

5-Isopropylimidazolidine-2,4-dione monohydrate
por: Abdel-Aziz, Alaa A.-M., et al.
Publicado: (2012)

Descriptors for Pentane-2,4-dione and Its Derivatives
por: Abraham, Michael H., et al.
Publicado: (2017)

3,8-Dimethylquinazoline-2,4(1H,3H)-dione
por: Qin, Wei-Yan, et al.
Publicado: (2011)

Method for detecting CoQ10 incorporation in the mitochondrial respiratory chain supercomplex
por: Sugawara, Kyousuke, et al.
Publicado: (2023)

The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS(n)-IT-TOF
por: Melton, Tyler C., et al.
Publicado: (2012)

Diiodido(1,10-phenanthroline-5,6-dione-κ(2) N,N′)mercury(II)
por: Ghaemi, Akbar, et al.
Publicado: (2011)

Dichloridobis(1,10-phenanthroline-5,6-dione-κ(2) N,N′)mercury(II)
por: Figueiras, Carlos A. L., et al.
Publicado: (2009)

1-Methyl-4H-3,1-benzoxazine-2,4(1H)dione
por: Deifel, Nicholas P., et al.
Publicado: (2010)

Serotonin transporter activity of imidazolidine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives in aspect of their acid–base properties
por: Zagórska, Agnieszka, et al.
Publicado: (2011)

Behavior of Hypochlorite and Chloramine-T
Publicado: (1918)

Docking, Synthesis and Anticonvulsant Activity of N-substituted Isoindoline-1,3-dione
por: Iman, Maryam, et al.
Publicado: (2017)

Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones
por: Łysakowska, Magdalena, et al.
Publicado: (2022)

5-Fluoro-1-(pentanoyl)pyrimidine-2,4(1H,3H)-dione
por: Lehmler, Hans-Joachim, et al.
Publicado: (2008)

6-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione monohydrate
por: Li, Gong-Chun, et al.
Publicado: (2010)

Tetraaqua(1,10-phenanthroline-5,6-dione-κ(2) N,N′)cobalt(II) dinitrate
por: Shi, Wen-Juan
Publicado: (2009)

Bis(1,10-phenanthroline-5,6-dione-κ(2) N,N′)silver(I) tetrafluoridoborate
por: Onuegbu, Jonathan, et al.
Publicado: (2009)

1-(4-Methoxyphenyl)imidazolidine-2,4-dione
por: Sun, Su-Xia, et al.
Publicado: (2010)

3-(3-Nitrobenzylidene)pentane-2,4-dione
por: Wu, Chuanbing
Publicado: (2008)

trans-5,6-Diphenylperhydropyran-2,4-dione
por: de Souza, Laura C., et al.
Publicado: (2009)

3-(Pyridin-4-ylthio)pentane-2,4-dione
por: Zhang, Qing-Fu, et al.
Publicado: (2011)

QSAR Study on Thiazolidine-2,4-dione Derivatives for Antihyperglycemic Activity
por: Prashantha Kumar, B. R., et al.
Publicado: (2008)

Pyrimidine 2,4-Diones in the Design of New HIV RT Inhibitors
por: Romeo, Roberto, et al.
Publicado: (2019)

Synthesis, SAR and in vitro therapeutic potentials of thiazolidine-2,4-diones
por: Sucheta, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jd78uoku18iorr2gmsneea3ira