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Nrf2-mediated anti-oxidant effects contribute to suppression of non-alcoholic steatohepatitis-associated hepatocellular carcinoma in murine model

The exact mechanisms of hepatocellular carcinoma development in non-alcoholic steatohepatitis remain unclear. In this study, we used a new class of high-fat diet, which could induce hepatocellular carcinoma development without the use of general chemical carcinogens or knockout mice. We investigated...

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Detalles Bibliográficos
Autores principales: Yamada, Shoji, Kimura, Masaki, Saito, Yoshimasa, Saito, Hidetsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160730/
https://www.ncbi.nlm.nih.gov/pubmed/30279623
http://dx.doi.org/10.3164/jcbn.17-125