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Age Influences Microglial Activation After Cuprizone-Induced Demyelination

Multiple sclerosis (MS) is a chronic inflammatory CNS disease, which causes demyelinated lesions and damages white and gray matter regions. Aging is a significant factor in the progression of MS, and microglia, the immune cells of the CNS tissue, play an important role in all disease stages. During...

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Detalles Bibliográficos
Autores principales: Klein, Barbara, Mrowetz, Heike, Barker, Conor Michael, Lange, Simona, Rivera, Francisco J., Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739/
https://www.ncbi.nlm.nih.gov/pubmed/30297998
http://dx.doi.org/10.3389/fnagi.2018.00278