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Age Influences Microglial Activation After Cuprizone-Induced Demyelination
Multiple sclerosis (MS) is a chronic inflammatory CNS disease, which causes demyelinated lesions and damages white and gray matter regions. Aging is a significant factor in the progression of MS, and microglia, the immune cells of the CNS tissue, play an important role in all disease stages. During...
Autores principales: | Klein, Barbara, Mrowetz, Heike, Barker, Conor Michael, Lange, Simona, Rivera, Francisco J., Aigner, Ludwig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739/ https://www.ncbi.nlm.nih.gov/pubmed/30297998 http://dx.doi.org/10.3389/fnagi.2018.00278 |
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