Evaluation of antibody fragment properties for near-infrared fluorescence imaging of HER3-positive cancer xenografts

In vivo imaging is influenced by the half-life, tissue penetration, biodistribution, and affinity of the imaging probe. Immunoglobulin G (IgG) is composed of discrete domains with known functions, providing a template for engineering antibody fragments with desired imaging properties. Here, we engin...

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Detalles Bibliográficos
Autores principales: El-Sayed, Ayman, Bernhard, Wendy, Barreto, Kris, Gonzalez, Carolina, Hill, Wayne, Pastushok, Landon, Fonge, Humphrey, Geyer, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160764/
https://www.ncbi.nlm.nih.gov/pubmed/30279742
http://dx.doi.org/10.7150/thno.24252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160764/
https://www.ncbi.nlm.nih.gov/pubmed/30279742
http://dx.doi.org/10.7150/thno.24252

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