Cargando…
Evaluation of antibody fragment properties for near-infrared fluorescence imaging of HER3-positive cancer xenografts
In vivo imaging is influenced by the half-life, tissue penetration, biodistribution, and affinity of the imaging probe. Immunoglobulin G (IgG) is composed of discrete domains with known functions, providing a template for engineering antibody fragments with desired imaging properties. Here, we engin...
Autores principales: | El-Sayed, Ayman, Bernhard, Wendy, Barreto, Kris, Gonzalez, Carolina, Hill, Wayne, Pastushok, Landon, Fonge, Humphrey, Geyer, C. Ronald |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160764/ https://www.ncbi.nlm.nih.gov/pubmed/30279742 http://dx.doi.org/10.7150/thno.24252 |
Ejemplares similares
-
Near infrared imaging of epidermal growth factor receptor positive xenografts in mice with domain I/II specific antibody fragments
por: Bernhard, Wendy, et al.
Publicado: (2019) -
Near infrared fluorescence imaging of EGFR expression in vivo using IRDye800CW-nimotuzumab
por: Bernhard, Wendy, et al.
Publicado: (2017) -
Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft
por: Hartimath, Siddesh V., et al.
Publicado: (2019) -
Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer
por: Solomon, Viswas Raja, et al.
Publicado: (2020) -
Evaluation of nimotuzumab Fab(2) as an optical imaging agent in EGFR positive cancers
por: Bernhard, Wendy, et al.
Publicado: (2023)