Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells

Butyrylcholinesterase (BChE) is the evolutionary counterpart to acetylcholinesterase (AChE). Both are expressed early in nervous system development prior to cholinergic synapse formation. The organophosphate pesticide chlorpyrifos (CPF) primarily exerts toxicity through the inhibition of AChE, which...

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Detalles Bibliográficos
Autores principales: Tiethof, Angela K., Richardson, Jason R., Hart, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160911/
https://www.ncbi.nlm.nih.gov/pubmed/30200437
http://dx.doi.org/10.3390/toxics6030052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160911/
https://www.ncbi.nlm.nih.gov/pubmed/30200437
http://dx.doi.org/10.3390/toxics6030052

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